SC6A3 Polyclonal Antibody

This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.

The SC6A3 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of SC6A3 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a unique sequence of the SC6A3 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the target protein, making it an ideal tool for various applications in research and diagnostics.

The SC6A3 Polyclonal Antibody is validated for use in Western blotting, immunohistochemistry, and immunofluorescence assays. It recognizes a single band of approximately 70 kDa in Western blot analysis of human brain lysates, which corresponds to the expected molecular weight of the SC6A3 protein. In addition, this antibody shows strong staining of SC6A3 in human brain tissue sections, indicating its suitability for use in immunohistochemistry.

The SC6A3 Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified from rabbit serum using protein A chromatography. It is provided in a liquid format, ready to use for various applications. The antibody is stable for long-term storage at -20°C and can be used for multiple experiments without loss of activity.

In summary, the SC6A3 Polyclonal Antibody is a reliable and high-quality reagent for the detection and quantification of SC6A3 protein in various biological samples. Its high specificity and sensitivity make it an ideal tool for research and diagnostic applications.