SAA1 Polyclonal Antibody

This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.

The SAA1 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of serum amyloid A1 (SAA1) protein. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the N-terminal region of human SAA1 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards SAA1 protein, making it an ideal tool for various applications in research and diagnostics.

The SAA1 Polyclonal Antibody is suitable for use in various immunoassays, including ELISA, Western blotting, and immunohistochemistry. It has been validated for use in human samples and has been shown to detect SAA1 protein in a variety of biological fluids, including serum, plasma, and synovial fluid. The antibody has also been shown to cross-react with SAA2 protein, which is highly homologous to SAA1.

This antibody is supplied as a purified IgG fraction, which has been affinity-purified from rabbit serum. It is provided in a liquid form, which can be easily diluted and used in various applications. The SAA1 Polyclonal Antibody is stable for long-term storage at -20°C and can be used for multiple experiments without loss of activity.

In summary, the SAA1 Polyclonal Antibody is a highly specific and sensitive immunological reagent that can be used for the detection and quantification of SAA1 protein in various biological samples. Its high affinity and specificity make it an ideal tool for research and diagnostic applications.