ROS1 Polyclonal Antibody

This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor.

The ROS1 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of ROS1 protein expression in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human ROS1 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards ROS1 protein, making it an ideal tool for various applications such as Western blotting, immunohistochemistry, and immunofluorescence.

The ROS1 Polyclonal Antibody is validated for use in human, mouse, and rat samples, and has been extensively tested for its specificity and sensitivity. It has been shown to detect endogenous ROS1 protein expression in various cancer cell lines and tissues, including lung cancer, glioblastoma, and cholangiocarcinoma. This antibody is also suitable for use in other research areas such as neuroscience, where ROS1 has been implicated in synaptic plasticity and memory formation.

The ROS1 Polyclonal Antibody is supplied as a purified IgG fraction, and is available in various sizes to suit different experimental needs. It is recommended to use this antibody at a dilution of 1:1000 for Western blotting, and 1:200 for immunohistochemistry and immunofluorescence. This antibody is also compatible with various detection systems, including chemiluminescence and fluorescence-based methods.

In summary, the ROS1 Polyclonal Antibody is a reliable and versatile tool for the detection and quantification of ROS1 protein expression in various biological samples. Its high specificity and sensitivity make it an ideal choice for researchers studying ROS1 function and its role in various diseases.