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SKU:BT-AP13880

Rock-1 Polyclonal Antibody

Rock-1 Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
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This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18.

The Rock-1 Polyclonal Antibody is a highly specific and sensitive antibody that has been designed for use in a wide range of research applications. This antibody has been developed using advanced techniques and is produced using high-quality materials to ensure consistent and reliable results.

The Rock-1 Polyclonal Antibody is designed to target the Rho-associated coiled-coil containing protein kinase 1 (Rock-1), which is a key regulator of actin cytoskeleton dynamics and cell migration. This antibody has been extensively validated for use in a variety of applications, including western blotting, immunohistochemistry, and immunofluorescence.

The Rock-1 Polyclonal Antibody is supplied in a convenient format, with a range of sizes available to suit your specific needs. This antibody is also provided with detailed instructions for use, ensuring that you can achieve optimal results with minimal effort.

Overall, the Rock-1 Polyclonal Antibody is an essential tool for researchers studying the role of Rock-1 in cellular processes such as cell migration, cell division, and cell adhesion. With its high specificity and sensitivity, this antibody is sure to provide reliable and reproducible results in your research.

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