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SKU:BT-AP13802

Ribosomal Protein S6(Phospho Ser240) Polyclonal Antibody

Ribosomal Protein S6(Phospho Ser240) Polyclonal Antibody

Regular price $275.00 USD
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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA.

The Ribosomal Protein S6 (Phospho Ser240) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of the phosphorylated form of Ribosomal Protein S6 at Ser240. This antibody is produced using a polyclonal approach, ensuring a high affinity and specificity towards the target protein.

The Ribosomal Protein S6 is a crucial component of the ribosome, playing a vital role in protein synthesis and cellular growth. Phosphorylation of Ribosomal Protein S6 at Ser240 has been implicated in various cellular processes, including cell proliferation, differentiation, and survival. Therefore, the detection and quantification of this phosphorylated form are of great importance in understanding the underlying mechanisms of these cellular processes.

This polyclonal antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated forms of Ribosomal Protein S6, ensuring accurate and reliable results.

The Ribosomal Protein S6 (Phospho Ser240) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments and ensuring cost-effectiveness. The antibody is manufactured under strict quality control standards, guaranteeing consistent performance and reproducibility.

In summary, the Ribosomal Protein S6 (Phospho Ser240) Polyclonal Antibody is a valuable tool for researchers studying cellular processes involving Ribosomal Protein S6 phosphorylation. Its high specificity, sensitivity, and versatility make it an ideal choice for various applications, enabling accurate and reliable detection and analysis of this important phosphorylated protein.

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