Ret(Phospho Tyr905) Polyclonal Antibody

This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.

The Ret(Phospho Tyr905) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Ret protein phosphorylated at tyrosine 905 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

The Ret protein plays a crucial role in various cellular processes, including cell survival, proliferation, and differentiation. Phosphorylation of tyrosine 905 residue is known to regulate the activation and signaling of Ret, making it an important target for research in the field of signal transduction and cancer biology.

The Ret(Phospho Tyr905) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated Ret protein in complex biological samples.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, ensuring cost-effectiveness and minimizing wastage. The Ret(Phospho Tyr905) Polyclonal Antibody is compatible with a wide range of experimental conditions and can be used in both basic research and clinical applications.

With its exceptional performance and reliability, the Ret(Phospho Tyr905) Polyclonal Antibody is an indispensable tool for scientists and researchers studying Ret signaling pathways and its implications in various diseases, particularly cancer.