RECQ4 Polyclonal Antibody

The protein encoded by this gene is a DNA helicase that belongs to the RecQ helicase family. DNA helicases unwind double-stranded DNA into single-stranded DNAs and may modulate chromosome segregation. This gene is predominantly expressed in thymus and testis. Mutations in this gene are associated with Rothmund-Thomson, RAPADILINO and Baller-Gerold syndromes.

The RECQ4 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of RECQ4 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human RECQ4 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the target protein, making it an ideal tool for various applications in research and diagnostics.

The RECQ4 Polyclonal Antibody is suitable for use in Western blotting, immunohistochemistry, and immunofluorescence assays. It has been validated for use in human, mouse, and rat samples, and has been shown to detect endogenous RECQ4 protein in various cell lines and tissues. This antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The RECQ4 Polyclonal Antibody is a valuable tool for researchers studying DNA repair mechanisms, as RECQ4 is a member of the RecQ helicase family involved in DNA repair and maintenance. It can also be used in clinical settings to detect RECQ4 protein expression in cancer cells, as RECQ4 has been implicated in the development and progression of various types of cancer.

Overall, the RECQ4 Polyclonal Antibody is a reliable and versatile reagent that can be used in a wide range of applications to detect and quantify RECQ4 protein expression in various biological samples. Its high specificity and sensitivity make it an essential tool for researchers and clinicians alike.