Rb(Phospho Thr821) Polyclonal Antibody

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

The RB(PHOSPHO THR821) Polyclonal Antibody is a highly specialized and meticulously developed product designed to cater to the needs of researchers and scientists in the field of molecular biology. This antibody is specifically designed to target and detect the phosphorylated form of the RB protein at threonine 821 residue.

With its exceptional specificity and sensitivity, this polyclonal antibody offers an invaluable tool for the investigation of RB protein phosphorylation and its role in various cellular processes. It enables researchers to gain deeper insights into the intricate mechanisms underlying cell cycle regulation, tumor suppression, and other crucial biological pathways.

Crafted with utmost precision and utilizing cutting-edge technology, this antibody guarantees reliable and reproducible results, ensuring the utmost accuracy in your experiments. Its high affinity and selectivity make it an ideal choice for a wide range of applications, including Western blotting, immunoprecipitation, and immunofluorescence.

Furthermore, this RB(PHOSPHO THR821) Polyclonal Antibody is manufactured under stringent quality control measures, adhering to the highest industry standards. Each batch undergoes rigorous testing to ensure consistent performance, guaranteeing the utmost reliability and reproducibility in your research.

In summary, the RB(PHOSPHO THR821) Polyclonal Antibody is an indispensable tool for researchers seeking to unravel the complexities of RB protein phosphorylation. Its exceptional specificity, sensitivity, and reliability make it an invaluable asset in the pursuit of scientific discovery and advancement in the field of molecular biology.