Rb(Phospho Ser795) Polyclonal Antibody

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

The RB(PHOSPHO SER795) Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of phosphorylated RB protein at serine 795 residue. This antibody has been meticulously developed and validated to ensure exceptional performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The RB(PHOSPHO SER795) Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling accurate and precise quantification of phosphorylated RB protein levels. It recognizes the phosphorylated serine 795 residue with high affinity, allowing for the detection of even low levels of phosphorylated RB protein in complex biological samples.

This antibody has been extensively tested and validated using a variety of cell lines and tissues, ensuring its reliability and reproducibility across different experimental conditions. It has been shown to exhibit minimal cross-reactivity with non-phosphorylated RB protein, further enhancing its specificity.

The RB(PHOSPHO SER795) Polyclonal Antibody is supplied as a purified and concentrated solution, ensuring optimal performance and ease of use. It is provided in a convenient size, allowing for multiple experiments without compromising its quality.

In summary, the RB(PHOSPHO SER795) Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of phosphorylated RB protein at serine 795 residue. Its exceptional sensitivity, specificity, and validated performance make it an invaluable asset for researchers studying RB protein phosphorylation and its role in various biological processes.