Rb(Phospho Ser608) Polyclonal Antibody

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

The RB(PHOSPHO SER608) Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of phosphorylated RB protein at serine 608 residue. This antibody has been meticulously developed and validated to ensure exceptional performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The RB(PHOSPHO SER608) Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling accurate and precise quantification of phosphorylated RB protein levels. Its high affinity for the phosphorylated serine 608 residue ensures minimal cross-reactivity with non-phosphorylated RB protein, resulting in reliable and reproducible results.

This antibody has been rigorously tested and validated using a variety of cell lysates and tissues, ensuring its suitability for a wide range of experimental settings. Its robust performance and consistent results make it an ideal choice for researchers studying RB protein phosphorylation and its role in various cellular processes.

The RB(PHOSPHO SER608) Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming and error-prone antibody dilutions. Its long shelf life and stability ensure consistent performance over an extended period, minimizing the need for frequent antibody replacements.

In summary, the RB(PHOSPHO SER608) Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of phosphorylated RB protein at serine 608 residue. Its exceptional sensitivity, specificity, and robust performance make it an invaluable asset for researchers investigating RB protein phosphorylation and its implications in various biological processes.