Rb(Phospho Ser249) Polyclonal Antibody

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

The RB(PHOSPHO SER249) Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of phosphorylated serine 249 residues in various biological samples. This antibody has been meticulously developed and rigorously validated to ensure optimal performance and accuracy in experimental settings.

With its polyclonal nature, this antibody exhibits a broad reactivity, allowing for the detection of phosphorylated serine 249 residues across a wide range of species. Its high affinity and specificity enable precise and sensitive detection, making it an ideal choice for researchers in the fields of molecular biology, biochemistry, and cell signaling.

The RB(PHOSPHO SER249) Polyclonal Antibody has been extensively tested and validated in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its exceptional performance in these techniques ensures reliable and reproducible results, facilitating the elucidation of phosphorylation events and their functional implications.

Furthermore, this antibody has been manufactured using state-of-the-art techniques and quality control measures to guarantee batch-to-batch consistency and reliability. Each lot is subjected to rigorous quality control tests to ensure optimal performance, specificity, and minimal cross-reactivity.

In summary, the RB(PHOSPHO SER249) Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of phosphorylated serine 249 residues. Its broad reactivity, exceptional performance in various applications, and stringent quality control measures make it an indispensable asset for researchers aiming to unravel the intricacies of phosphorylation events in biological systems.