Skip to product information
1 of 1

BT Lab

SKU:BT-AP13529

Raf-1(Phospho Tyr341) Polyclonal Antibody

Raf-1(Phospho Tyr341) Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
Host
Ab type

This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.

Introducing the RAF-1 Phospho-Tyr341 Polyclonal Antibody, meticulously developed by BT Lab, a renowned name in the field of life sciences. This cutting-edge antibody is designed to specifically target and detect the phosphorylated form of RAF-1 at Tyr341, enabling researchers to delve deeper into the intricate mechanisms of cellular signaling pathways.

Crafted with utmost precision and utilizing state-of-the-art technology, the RAF-1 Phospho-Tyr341 Polyclonal Antibody exhibits exceptional sensitivity and specificity, ensuring accurate and reliable results. Its high affinity for the phosphorylated form of RAF-1 guarantees minimal cross-reactivity, thereby enhancing the precision of experimental outcomes.

This antibody is an invaluable tool for scientists engaged in various research areas, including cancer biology, signal transduction, and kinase signaling pathways. By facilitating the investigation of RAF-1 phosphorylation at Tyr341, it opens up new avenues for understanding the role of this critical protein in cellular processes and disease progression.

The RAF-1 Phospho-Tyr341 Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for seamless integration into laboratory workflows. Its robust performance is further complemented by its compatibility with a wide range of applications, including Western blotting, immunoprecipitation, and immunofluorescence.

Rest assured, this antibody has undergone rigorous quality control measures to ensure its reliability and reproducibility. Each batch is meticulously tested to meet the highest standards, guaranteeing consistent performance and accurate results.

In summary, the RAF-1 Phospho-Tyr341 Polyclonal Antibody by BT Lab is a cutting-edge research tool that empowers scientists to unravel the complexities of cellular signaling pathways. With its exceptional sensitivity, specificity, and compatibility with various applications, it is an indispensable asset for researchers striving to advance their understanding of RAF-1 phosphorylation and its implications in disease biology.

View full details