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BT Lab

SKU:BT-AP13528

Raf-1(Phospho Thr269) Polyclonal Antibody

Raf-1(Phospho Thr269) Polyclonal Antibody

Regular price $275.00 USD
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This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.

Introducing the RAF-1 Phospho-Thr269 Polyclonal Antibody, meticulously developed by BT Lab, a renowned name in the field of biotechnology. This cutting-edge antibody is designed to specifically target and detect the phosphorylated form of RAF-1 at threonine 269 residue, enabling researchers to delve deeper into the intricate world of cellular signaling pathways.

Crafted with utmost precision and expertise, the RAF-1 Phospho-Thr269 Polyclonal Antibody exhibits exceptional sensitivity and specificity, ensuring accurate and reliable results. Its high affinity towards the phosphorylated RAF-1 protein guarantees optimal performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

With its advanced formulation, this antibody offers unparalleled versatility, making it an invaluable tool for scientists and researchers engaged in the study of signal transduction pathways, cancer biology, and drug discovery. Its ability to precisely recognize and bind to the phosphorylated RAF-1 protein at threonine 269 residue opens up new avenues for investigating the intricate mechanisms underlying cellular processes.

The RAF-1 Phospho-Thr269 Polyclonal Antibody is meticulously manufactured using state-of-the-art techniques and undergoes rigorous quality control measures to ensure consistent and reproducible results. Its exceptional performance is a testament to the unwavering commitment of BT Lab to deliver products of the highest caliber.

In summary, the RAF-1 Phospho-Thr269 Polyclonal Antibody by BT Lab is a groundbreaking tool that empowers researchers to unravel the complexities of cellular signaling pathways. With its exceptional sensitivity, specificity, and versatility, this antibody is poised to revolutionize the field of molecular biology and contribute to advancements in various scientific disciplines.

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