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BT Lab

SKU:BT-AP13523

Raf-1(Phospho Ser301) Polyclonal Antibody

Raf-1(Phospho Ser301) Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
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This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.

Introducing the RAF-1 Phospho-Ser301 Polyclonal Antibody, meticulously developed by BT Lab, a renowned name in the field of life sciences. This cutting-edge antibody is designed to specifically target and detect the phosphorylated form of RAF-1 at serine 301, enabling researchers to delve deeper into the intricate mechanisms of cellular signaling pathways.

Crafted with utmost precision and utilizing state-of-the-art technology, the RAF-1 Phospho-Ser301 Polyclonal Antibody exhibits exceptional sensitivity and specificity, ensuring accurate and reliable results. Its high affinity for the phosphorylated serine 301 residue of RAF-1 guarantees optimal performance in various applications, including immunohistochemistry, western blotting, and immunofluorescence.

With its robust formulation, this antibody offers unparalleled versatility, making it an invaluable tool for elucidating the role of RAF-1 phosphorylation in diverse biological processes. Whether investigating signal transduction cascades, studying cellular responses to external stimuli, or exploring the intricate interplay between proteins, the RAF-1 Phospho-Ser301 Polyclonal Antibody empowers researchers to unlock new frontiers in molecular biology.

Furthermore, the RAF-1 Phospho-Ser301 Polyclonal Antibody is meticulously validated to ensure consistent and reproducible results. Rigorous quality control measures are implemented throughout the production process, guaranteeing batch-to-batch consistency and reliability. This antibody is manufactured in compliance with the highest industry standards, adhering to strict quality assurance protocols.

To facilitate ease of use, the RAF-1 Phospho-Ser301 Polyclonal Antibody is provided in a user-friendly format, accompanied by comprehensive instructions for optimal handling and storage. Its long shelf life ensures prolonged usability, minimizing the need for frequent reordering and ensuring cost-effectiveness for research laboratories.

In summary, the RAF-1 Phospho-Ser301 Polyclonal Antibody by BT Lab is a cutting-edge research tool that empowers scientists to unravel the complexities of cellular signaling pathways. With its exceptional sensitivity, specificity, and versatility, this antibody is poised to revolutionize the field of molecular biology, enabling groundbreaking discoveries and advancing scientific knowledge.

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