RAB8A Polyclonal Antibody

The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malign

The RAB8A Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of RAB8A protein expression in various biological samples. This antibody is produced using advanced immunization techniques, resulting in a high affinity and specificity towards RAB8A.

RAB8A is a member of the RAS oncogene family and plays a crucial role in intracellular vesicle trafficking and protein transport. It is involved in the regulation of various cellular processes, including cell polarization, cytokinesis, and ciliogenesis. Dysregulation of RAB8A has been implicated in several diseases, including cancer and neurodevelopmental disorders.

The RAB8A Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of RAB8A protein expression in both normal and diseased tissues.

This antibody is supplied as a liquid formulation, allowing for easy handling and storage. It is provided in a convenient size, ensuring cost-effectiveness and minimizing wastage. The RAB8A Polyclonal Antibody is compatible with a wide range of secondary antibodies and detection systems, facilitating its integration into existing experimental protocols.

With its exceptional performance and versatility, the RAB8A Polyclonal Antibody is an indispensable tool for researchers studying RAB8A biology and its implications in various physiological and pathological processes. Its reliable and reproducible results make it an ideal choice for both basic research and clinical applications.