PTEN(Phospho Ser370) Polyclonal Antibody

This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. The use of a non-canonical (CUG) upstream initiation site produces a longer isoform that initiates translation with a leucine, and is thought to be preferentially associated with the mitochondrial inner membrane. This longer isoform may help regulate ener

Introducing the PTEN Phospho-Ser370 Polyclonal Antibody, meticulously developed by BT Lab, a renowned name in the field of life sciences. This cutting-edge antibody is designed to specifically target and detect the phosphorylated form of PTEN at serine 370, enabling researchers to delve deeper into the intricate mechanisms of cellular signaling pathways.

Crafted with utmost precision and utilizing state-of-the-art technology, this antibody exhibits exceptional sensitivity and specificity, ensuring accurate and reliable results. Its polyclonal nature allows for enhanced binding affinity, facilitating robust detection of PTEN phosphorylation at serine 370 across a wide range of experimental conditions.

The PTEN Phospho-Ser370 Polyclonal Antibody is meticulously validated through rigorous quality control measures, guaranteeing optimal performance and reproducibility. Its versatility is further enhanced by its compatibility with various applications, including Western blotting, immunohistochemistry, and immunofluorescence, enabling comprehensive analysis of PTEN phosphorylation in diverse experimental setups.

With its user-friendly protocol and straightforward implementation, this antibody offers researchers a seamless experience, saving valuable time and resources. Its exceptional performance, coupled with its cost-effectiveness, makes it an indispensable tool for both academic and industrial laboratories alike.

Trust in the PTEN Phospho-Ser370 Polyclonal Antibody by BT Lab to unlock new insights into the intricate world of cellular signaling, empowering you to make groundbreaking discoveries in the realm of life sciences.