PSMD9 Polyclonal Antibody

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene.

The PSMD9 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of PSMD9 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human PSMD9 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards PSMD9 protein, making it an ideal tool for various applications such as Western blotting, immunohistochemistry, and immunofluorescence.

The PSMD9 Polyclonal Antibody is purified using a combination of protein A and peptide affinity chromatography, ensuring high purity and minimal cross-reactivity with other proteins. This antibody has been extensively validated for its specificity and sensitivity, and has been shown to detect endogenous levels of PSMD9 protein in various cell lines and tissues.

The PSMD9 Polyclonal Antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in various sizes to suit different experimental needs. This antibody is suitable for use in both research and diagnostic applications, and is an essential tool for studying the role of PSMD9 protein in various biological processes.