PSD13 Polyclonal Antibody

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.  An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described.

The PSD13 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of PSD13 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human PSD13 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards PSD13 protein, making it an ideal tool for various applications in research and diagnostics.

The PSD13 Polyclonal Antibody is purified using a combination of protein A and peptide affinity chromatography, ensuring high purity and minimal cross-reactivity with other proteins. This antibody is suitable for use in various immunoassays, including Western blotting, immunohistochemistry, and ELISA. It has been validated for use in human, mouse, and rat samples, making it a versatile tool for researchers working with different model organisms.

The PSD13 Polyclonal Antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in different sizes to meet the needs of different applications and experimental setups. This antibody is manufactured under strict quality control standards to ensure consistent performance and reproducibility.

In summary, the PSD13 Polyclonal Antibody is a reliable and high-quality reagent for the detection and quantification of PSD13 protein in various biological samples. Its high specificity, sensitivity, and versatility make it an essential tool for researchers working in the fields of neuroscience, cell biology, and molecular biology.