PRAK(Phospho Thr182) Polyclonal Antibody

The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.

Introducing the PRAK(PHOSPHO THR182) Polyclonal Antibody, a highly specific and sensitive tool for the detection of phosphorylated PRAK protein. This antibody has been rigorously tested and validated for use in a variety of applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The PRAK(PHOSPHO THR182) Polyclonal Antibody is produced using state-of-the-art techniques and high-quality materials, ensuring consistent and reliable results. It is designed to recognize and bind specifically to the phosphorylated threonine 182 residue of the PRAK protein, making it an ideal tool for studying the regulation and function of this important signaling molecule.

This antibody is supplied in a convenient and easy-to-use format, with clear instructions for optimal performance. It is suitable for use in a wide range of research applications, including cancer biology, cell signaling, and drug discovery.

In summary, the PRAK(PHOSPHO THR182) Polyclonal Antibody is a valuable tool for researchers seeking to investigate the role of PRAK in cellular signaling pathways. Its high specificity and sensitivity make it an ideal choice for a variety of applications, and its consistent performance ensures reliable and reproducible results.