PON2 Polyclonal Antibody

This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.

The PON2 Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for the detection of Paraoxonase 2 (PON2) protein. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human PON2 protein. The PON2 Polyclonal Antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and ELISA.

The PON2 protein is a member of the paraoxonase family of enzymes that are involved in the metabolism of lipids and lipoproteins. PON2 has been implicated in a variety of physiological processes, including the regulation of oxidative stress, inflammation, and atherosclerosis. The PON2 Polyclonal Antibody is an essential tool for researchers studying the role of PON2 in these processes.

The PON2 Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using a protein A column. This antibody has been tested and validated for use in a variety of species, including human, mouse, and rat. The PON2 Polyclonal Antibody is provided in a liquid format and can be stored at -20°C for long-term use.

In summary, the PON2 Polyclonal Antibody is a highly specific and sensitive antibody that is essential for the detection of PON2 protein in various applications. This antibody is produced using state-of-the-art techniques and has been extensively validated for use in research. Researchers can rely on the PON2 Polyclonal Antibody to provide accurate and reliable results in their studies of PON2 protein.