POLH Polyclonal Antibody

This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.

Introducing the POLH Polyclonal Antibody, a cutting-edge scientific tool designed to revolutionize research in the field of molecular biology. This meticulously crafted antibody is meticulously engineered to target and detect the POLH protein, a crucial component involved in DNA repair processes.

The POLH Polyclonal Antibody boasts exceptional specificity and sensitivity, ensuring accurate and reliable results in a wide range of applications. Its high affinity for the POLH protein enables precise identification and quantification, facilitating comprehensive analysis of DNA repair mechanisms.

Crafted with utmost precision, this antibody undergoes rigorous quality control measures to guarantee optimal performance and reproducibility. Its exceptional stability and long shelf life ensure consistent results, making it an indispensable asset for laboratories and research institutions.

The POLH Polyclonal Antibody is compatible with various experimental techniques, including Western blotting, immunohistochemistry, and immunofluorescence. Its versatility allows for seamless integration into diverse research protocols, empowering scientists to explore the intricate workings of DNA repair pathways with unparalleled accuracy.

With its state-of-the-art formulation and unrivaled performance, the POLH Polyclonal Antibody sets a new standard in molecular biology research. Elevate your scientific endeavors and unlock new insights into DNA repair mechanisms with this remarkable tool.