PMVK Polyclonal Antibody

This gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis.

The PMVK Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of PMVK protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human PMVK protein. The resulting polyclonal antibody exhibits high affinity and specificity towards PMVK protein, making it an ideal tool for various applications such as Western blotting, ELISA, immunohistochemistry, and immunofluorescence.

The PMVK Polyclonal Antibody is purified using a combination of protein A and peptide affinity chromatography, ensuring high purity and minimal cross-reactivity with other proteins. This antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is recommended to store the antibody at -20°C for long-term storage and avoid repeated freeze-thaw cycles.

The PMVK Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various biological samples, including human, mouse, and rat tissues. It has been shown to detect endogenous PMVK protein in various cell lines and tissues with high specificity and sensitivity. This antibody is an essential tool for researchers studying the role of PMVK protein in various biological processes, including cholesterol biosynthesis, peroxisome biogenesis, and lipid metabolism.

In summary, the PMVK Polyclonal Antibody is a highly specific and sensitive immunological reagent that is ideal for the detection and quantification of PMVK protein in various biological samples. Its high affinity and specificity make it an essential tool for researchers studying the role of PMVK protein in various biological processes.