PLIN2 Polyclonal Antibody

The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene.

The PLIN2 Polyclonal Antibody, offered by Dana Biosciences, is a highly specific and sensitive tool for the detection of Perilipin-2 (PLIN2) protein in various biological samples. This antibody has been rigorously tested and validated for use in Western blotting, immunohistochemistry, and immunofluorescence applications.

The PLIN2 protein is a member of the Perilipin family of lipid droplet-associated proteins, which play a crucial role in regulating lipid metabolism and storage in adipocytes and other cells. Abnormal expression or function of PLIN2 has been implicated in various metabolic disorders, including obesity, diabetes, and non-alcoholic fatty liver disease.

The PLIN2 Polyclonal Antibody is produced using high-quality immunogens and advanced purification techniques to ensure maximum specificity and minimal cross-reactivity. It has been validated for use in a wide range of species, including human, mouse, rat, and others.

This antibody is supplied in a convenient format, with various sizes and concentrations available to suit different experimental needs. It is also backed by Dana Biosciences' expert technical support and quality guarantee, ensuring reliable and reproducible results every time.

In summary, the PLIN2 Polyclonal Antibody from Dana Biosciences is a valuable tool for researchers studying lipid metabolism and related disorders. Its high specificity, sensitivity, and versatility make it an ideal choice for a wide range of applications in both basic and clinical research.