PKC(Phospho Thr497) Polyclonal Antibody

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

The PKC(PHOSPHO THR497) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of protein kinase C (PKC) phosphorylated at threonine 497. This antibody is produced through a rigorous process of immunization using a synthetic phosphopeptide corresponding to the phosphorylated threonine 497 region of PKC.

With its exceptional sensitivity and specificity, this polyclonal antibody enables researchers to investigate the phosphorylation status of PKC at threonine 497 in various biological samples. It is suitable for use in a wide range of applications, including Western blotting, immunoprecipitation, and immunohistochemistry.

The PKC(PHOSPHO THR497) Polyclonal Antibody exhibits minimal cross-reactivity with non-phosphorylated PKC and other related proteins, ensuring accurate and reliable results. It is produced using state-of-the-art techniques and undergoes stringent quality control measures to guarantee batch-to-batch consistency and optimal performance.

This antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is recommended to store the antibody at -20°C for long-term stability. Prior to use, it is advised to briefly centrifuge the vial to ensure proper mixing.

In summary, the PKC(PHOSPHO THR497) Polyclonal Antibody is a valuable tool for researchers studying PKC phosphorylation at threonine 497. Its high specificity, sensitivity, and reliability make it an essential component in various research applications, facilitating a deeper understanding of PKC signaling pathways and their implications in cellular processes.