PHX2B Polyclonal Antibody

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome.

The PHX2B polyclonal antibody is a highly specific and reliable tool for various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a unique epitope of the PHX2B protein. It has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence assays.

The PHX2B polyclonal antibody exhibits exceptional performance in detecting endogenous levels of PHX2B protein in various tissues and cell lines. It recognizes a band of approximately 40 kDa in Western blot analysis, confirming its high affinity and selectivity. Furthermore, this antibody demonstrates minimal cross-reactivity with other related proteins, ensuring accurate and reliable results.

In immunohistochemistry and immunofluorescence applications, the PHX2B polyclonal antibody displays strong and specific staining patterns, enabling precise localization of the PHX2B protein within cells and tissues. Its excellent signal-to-noise ratio ensures clear and distinct visualization, facilitating detailed analysis and interpretation of experimental data.

The PHX2B polyclonal antibody is supplied as a purified and concentrated solution, ensuring optimal performance and long-term stability. It is provided in a convenient format, allowing for easy handling and storage. Each batch of antibody undergoes rigorous quality control procedures to guarantee consistent and reproducible results.

In summary, the PHX2B polyclonal antibody is a valuable tool for researchers studying the PHX2B protein. Its high specificity, sensitivity, and reliability make it an ideal choice for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Trust in the PHX2B polyclonal antibody to enhance your research and advance scientific knowledge in the field.