PDGFRb(Phospho-Tyr857) Polyclonal Antibody

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

The PDGFRb(Phospho-Tyr857) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of PDGFRb protein phosphorylated at tyrosine 857 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

The PDGFRb protein plays a crucial role in various cellular processes, including cell growth, differentiation, and migration. Phosphorylation of tyrosine 857 residue is known to regulate the activation and signaling of PDGFRb, making it an important target for research in the field of cell biology and signal transduction.

This polyclonal antibody is rigorously validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of PDGFRb phosphorylated at tyrosine 857 residue.

The PDGFRb(Phospho-Tyr857) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing wastage. The antibody is also compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.

With its exceptional performance and versatility, the PDGFRb(Phospho-Tyr857) Polyclonal Antibody is an indispensable tool for researchers and scientists studying PDGFRb signaling pathways and its implications in various diseases, including cancer and cardiovascular disorders.