PDGFR-beta(Phospho Tyr771) Polyclonal Antibody

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

The PDGFR-beta(Phospho Tyr771) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of PDGFR-beta protein phosphorylated at tyrosine 771 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

PDGFR-beta, also known as platelet-derived growth factor receptor beta, is a transmembrane receptor tyrosine kinase that plays a crucial role in various cellular processes, including cell proliferation, differentiation, and migration. Phosphorylation of PDGFR-beta at tyrosine 771 residue is known to be involved in the activation of downstream signaling pathways, leading to the regulation of cellular functions.

The PDGFR-beta(Phospho Tyr771) Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate detection and quantification of phosphorylated PDGFR-beta protein in complex biological samples.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size of 100 µg, ensuring sufficient quantity for multiple experiments. The PDGFR-beta(Phospho Tyr771) Polyclonal Antibody is manufactured under strict quality control standards, guaranteeing consistent and reliable results.

Researchers and scientists in the fields of cell biology, molecular biology, and cancer research will greatly benefit from the PDGFR-beta(Phospho Tyr771) Polyclonal Antibody, as it enables the investigation of PDGFR-beta phosphorylation and its role in various cellular processes.