PDGFR-alpha(Phospho Tyr762) Polyclonal Antibody

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

The PDGFR-alpha(Phospho Tyr762) Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of PDGFR-alpha protein phosphorylated at tyrosine 762. This antibody has been rigorously validated for use in various applications, including Western blotting, immunoprecipitation, and immunohistochemistry.

PDGFR-alpha is a receptor tyrosine kinase that plays a crucial role in cell growth, proliferation, and differentiation. Phosphorylation of tyrosine 762 is known to regulate the activation and downstream signaling of PDGFR-alpha. Therefore, the PDGFR-alpha(Phospho Tyr762) Polyclonal Antibody provides a valuable means to study the functional significance of this phosphorylation event.

This antibody has been produced using high-quality materials and state-of-the-art techniques to ensure optimal performance and reproducibility. It exhibits exceptional specificity, with minimal cross-reactivity to other proteins, allowing for accurate and reliable results. Additionally, it demonstrates high sensitivity, enabling the detection of low levels of phosphorylated PDGFR-alpha.

The PDGFR-alpha(Phospho Tyr762) Polyclonal Antibody is supplied as a liquid formulation, making it convenient and easy to use. It is provided in a vial with an appropriate amount for multiple experiments, ensuring cost-effectiveness and minimizing waste.

In summary, the PDGFR-alpha(Phospho Tyr762) Polyclonal Antibody is a reliable and efficient tool for the investigation of PDGFR-alpha phosphorylation at tyrosine 762. Its high specificity, sensitivity, and ease of use make it an ideal choice for researchers studying the role of PDGFR-alpha in various biological processes.