PDGFR-alpha(Phospho Tyr754) Polyclonal Antibody

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

The PDGFR-alpha(Phospho Tyr754) Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of PDGFR-alpha protein phosphorylated at tyrosine 754. This antibody has been rigorously validated for use in various applications, including Western blotting, immunoprecipitation, and immunohistochemistry.

PDGFR-alpha is a receptor tyrosine kinase that plays a crucial role in cell growth, proliferation, and differentiation. Phosphorylation of tyrosine 754 is known to regulate the activation and downstream signaling of PDGFR-alpha. Therefore, the PDGFR-alpha(Phospho Tyr754) Polyclonal Antibody provides a valuable means to study the functional significance of this phosphorylation event.

This antibody has been produced using high-quality materials and advanced techniques to ensure exceptional performance and reproducibility. It exhibits high affinity and specificity towards the phosphorylated form of PDGFR-alpha at tyrosine 754, while showing minimal cross-reactivity with non-phosphorylated PDGFR-alpha or other related proteins.

The PDGFR-alpha(Phospho Tyr754) Polyclonal Antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It has been optimized for use in a variety of experimental conditions and can be used with confidence in both basic research and clinical applications.

In summary, the PDGFR-alpha(Phospho Tyr754) Polyclonal Antibody is a reliable and versatile tool for the investigation of PDGFR-alpha phosphorylation at tyrosine 754. Its exceptional sensitivity and specificity make it an ideal choice for researchers and scientists working in the fields of cell biology, signal transduction, and cancer research.