Skip to product information
1 of 1

BT Lab

SKU:BT-AP12858

PDC6I Polyclonal Antibody

PDC6I Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
Host
Ab type

This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15.

The PDC6I Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for use in a variety of research applications. This antibody has been raised against a synthetic peptide corresponding to the C-terminal region of the human PDC6I protein, and has been extensively validated for use in Western blotting, immunohistochemistry, and immunofluorescence assays.

The PDC6I Polyclonal Antibody is produced using state-of-the-art techniques and is purified to a high degree of purity, ensuring that it is free from contaminants and other impurities that may interfere with its performance. This antibody has been shown to exhibit excellent specificity and sensitivity, making it an ideal tool for the detection and quantification of PDC6I protein in a variety of biological samples.

In addition to its high performance, the PDC6I Polyclonal Antibody is also highly versatile, and can be used in a wide range of applications, including basic research, drug discovery, and clinical diagnostics. Whether you are studying the role of PDC6I in disease pathogenesis, or developing new therapies for the treatment of PDC6I-related disorders, this antibody is an essential tool for your research.

Overall, the PDC6I Polyclonal Antibody is a highly reliable and effective tool for the detection and quantification of PDC6I protein in a variety of biological samples. With its high specificity, sensitivity, and versatility, this antibody is an essential tool for any researcher working in the field of PDC6I biology.

View full details