PCP Polyclonal Antibody

This gene encodes a member of the peptidase S28 family of serine exopeptidases. The encoded preproprotein is proteolytically processed to generate the mature lysosomal prolylcarboxypeptidase. This enzyme cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. A pseudogene of this gene has been identified on chromosome 2. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

The PCP Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of PCP (phencyclidine) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the PCP protein.

The PCP Polyclonal Antibody exhibits exceptional affinity and selectivity towards PCP, ensuring accurate and reliable results in a wide range of applications, including ELISA, Western blotting, and immunohistochemistry. It has been extensively validated and optimized to provide consistent and reproducible performance.

With its superior sensitivity, the PCP Polyclonal Antibody allows for the detection of PCP at low concentrations, making it an invaluable tool for researchers and clinicians working in the fields of toxicology, pharmacology, and forensic science. Its robust performance and high specificity ensure minimal cross-reactivity with structurally related compounds, enhancing the accuracy of PCP detection.

The PCP Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is available in various sizes to accommodate different experimental needs. Each batch is quality-controlled to ensure batch-to-batch consistency and reliability.

In summary, the PCP Polyclonal Antibody is a highly specific and sensitive immunological reagent that enables accurate and reliable detection and quantification of PCP in various biological samples. Its exceptional performance, high specificity, and ease of use make it an essential tool for researchers and professionals in the fields of toxicology, pharmacology, and forensic science.