PCBP1 Polyclonal Antibody

This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. Th

The PCBP1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of PCBP1 protein expression in various biological samples. This antibody is produced using advanced recombinant technology, ensuring high purity and quality.

PCBP1, also known as poly(rC)-binding protein 1, is a multifunctional RNA-binding protein that plays a crucial role in post-transcriptional regulation of gene expression. It is involved in various cellular processes, including mRNA stability, translation, and localization. Dysregulation of PCBP1 has been implicated in several diseases, including cancer and neurological disorders.

The PCBP1 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various experimental techniques, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other related proteins, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is provided in a ready-to-use format, eliminating the need for additional reagents or preparation steps. The PCBP1 Polyclonal Antibody is suitable for both research and diagnostic applications, enabling scientists and clinicians to gain valuable insights into the role of PCBP1 in various biological processes and diseases.

In summary, the PCBP1 Polyclonal Antibody is a highly specific and sensitive tool that enables the detection and analysis of PCBP1 protein expression. With its advanced recombinant technology, extensive validation, and convenient formulation, this antibody is an essential asset for researchers and clinicians in their quest for understanding the intricate mechanisms of gene regulation and disease pathogenesis.