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SKU:BT-AP12752
PAK alpha/beta / gamma(Phospho Thr423/402/421) Polyclonal Antibody
PAK alpha/beta / gamma(Phospho Thr423/402/421) Polyclonal Antibody
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This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
The PAK alpha/beta/gamma (Phospho Thr423/402/421) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of PAK alpha, beta, and gamma isoforms. This antibody is raised against the phosphorylated forms of PAK at Thr423, Thr402, and Thr421 residues, enabling the identification and quantification of the activated state of PAK proteins.
With its polyclonal nature, this antibody exhibits a broad reactivity towards PAK alpha, beta, and gamma isoforms, making it an ideal choice for researchers studying the diverse functions and signaling pathways associated with these proteins. The high affinity and specificity of this antibody ensure accurate and reliable results in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.
The PAK alpha/beta/gamma (Phospho Thr423/402/421) Polyclonal Antibody is manufactured using advanced techniques and quality-controlled processes to ensure consistent performance and reproducibility. It is supplied in a convenient format, allowing for easy handling and storage.
In summary, the PAK alpha/beta/gamma (Phospho Thr423/402/421) Polyclonal Antibody is a valuable tool for researchers investigating the role of PAK proteins in cellular processes and signaling pathways. Its high specificity, sensitivity, and versatility make it an essential component of any laboratory studying protein phosphorylation and its implications in various biological contexts.
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