PABP2 Polyclonal Antibody

This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.

The PABP2 Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for the detection of PABP2 protein in various biological samples. This antibody has been produced using high-quality polyclonal antibodies that have been purified and characterized to ensure optimal performance in a range of applications.

The PABP2 Polyclonal Antibody has been extensively validated for use in Western blotting, immunohistochemistry, and immunofluorescence assays. It has been shown to exhibit excellent specificity and sensitivity, with minimal cross-reactivity to other proteins.

This antibody is ideal for researchers studying the role of PABP2 in various cellular processes, including mRNA translation, RNA metabolism, and gene expression regulation. It can also be used for diagnostic purposes in clinical settings.

The PABP2 Polyclonal Antibody is supplied in a convenient format, with a range of sizes available to suit different experimental needs. It has been rigorously tested to ensure consistent performance, and is backed by our quality guarantee.

Overall, the PABP2 Polyclonal Antibody is a reliable and effective tool for the detection of PABP2 protein in a range of applications, making it an essential reagent for researchers and clinicians alike.