p47-phox(Phospho Ser359) Polyclonal Antibody

The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.

The p47-phox(Phospho Ser359) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of p47-phox protein phosphorylated at Ser359. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

The p47-phox protein plays a crucial role in the regulation of reactive oxygen species (ROS) production by the NADPH oxidase complex. Phosphorylation of p47-phox at Ser359 has been shown to be an important post-translational modification that regulates the activation and function of the NADPH oxidase complex.

This polyclonal antibody has been extensively validated for its specificity and sensitivity in various experimental settings, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated p47-phox protein, ensuring accurate and reliable results.

The p47-phox(Phospho Ser359) Polyclonal Antibody is supplied as a liquid formulation in a convenient size of 100 µg. It is provided in a ready-to-use format, eliminating the need for additional preparation steps. The antibody is suitable for use in both research and diagnostic applications, enabling the investigation of p47-phox phosphorylation in various biological samples.

With its high specificity, sensitivity, and reliability, the p47-phox(Phospho Ser359) Polyclonal Antibody is an essential tool for researchers and clinicians studying the role of p47-phox phosphorylation in oxidative stress, inflammation, and various diseases.