p38 Polyclonal Antibody

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding d

The p38 Polyclonal Antibody is a highly specific and sensitive antibody that has been designed to detect and quantify the presence of p38 protein in various biological samples. This antibody has been extensively validated for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The p38 Polyclonal Antibody has been produced using high-quality materials and state-of-the-art techniques to ensure maximum specificity and sensitivity. It has been rigorously tested to ensure that it does not cross-react with other proteins, ensuring accurate and reliable results.

This antibody is suitable for use in a variety of research applications, including studies of cellular signaling pathways, inflammation, and stress response. It is also an essential tool for researchers studying the role of p38 in various diseases, including cancer, arthritis, and cardiovascular disease.

Overall, the p38 Polyclonal Antibody is a highly reliable and effective tool for researchers looking to study the function and regulation of p38 protein in various biological systems. Its high specificity and sensitivity make it an essential tool for any laboratory conducting research in this area.