p300 (Acetyl Lys1558/Acetyl Lys1560) Polyclonal Antibody

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

Introducing the p300 (Acetyl Lys1558/Acetyl Lys1560) Polyclonal Antibody, a highly specialized and meticulously crafted product designed to cater to the needs of researchers and scientists in the field of molecular biology. This antibody, derived from polyclonal sources, exhibits exceptional specificity and sensitivity, making it an invaluable tool for various applications, including immunoprecipitation, Western blotting, and immunofluorescence.

The p300 (Acetyl Lys1558/Acetyl Lys1560) Polyclonal Antibody is meticulously developed using state-of-the-art techniques, ensuring the highest level of quality and reliability. It specifically targets the acetylated lysine residues at positions 1558 and 1560 of the p300 protein, enabling precise detection and analysis of acetylation events in cellular processes.

With its exceptional affinity and selectivity, this antibody offers researchers an unparalleled opportunity to investigate the intricate mechanisms underlying protein acetylation. By facilitating the identification and characterization of acetylated proteins, the p300 (Acetyl Lys1558/Acetyl Lys1560) Polyclonal Antibody opens new avenues for understanding the role of acetylation in cellular signaling pathways, gene expression regulation, and disease progression.

Furthermore, this antibody demonstrates remarkable versatility, exhibiting robust performance across a wide range of experimental techniques. Its compatibility with immunoprecipitation allows for efficient isolation and enrichment of acetylated proteins, while its suitability for Western blotting ensures accurate and reliable protein detection. Additionally, its application in immunofluorescence enables precise visualization and localization of acetylated proteins within cellular compartments.

In summary, the p300 (Acetyl Lys1558/Acetyl Lys1560) Polyclonal Antibody represents a cutting-edge tool that empowers researchers to delve deeper into the intricate world of protein acetylation. With its exceptional specificity, sensitivity, and versatility, this antibody is poised to revolutionize the field of molecular biology, facilitating groundbreaking discoveries and advancing our understanding of cellular processes.