NUP62 Polyclonal Antibody

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Multiple transcript variants of this gene encode a single protein isoform.

The NUP62 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of NUP62 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the N-terminal region of human NUP62 protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid solution in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The NUP62 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes a single band of approximately 62 kDa in Western blot analysis of human cell lysates, which corresponds to the expected molecular weight of NUP62 protein. In addition, the antibody shows strong staining of the nuclear envelope in immunohistochemistry and immunofluorescence assays, indicating its high specificity for NUP62 protein.

This antibody is an essential tool for researchers studying the function and localization of NUP62 protein in various biological processes, including nuclear transport, gene expression, and cell division. Its high specificity and sensitivity make it an ideal choice for detecting NUP62 protein in complex biological samples, such as tissue lysates and cell extracts. The NUP62 Polyclonal Antibody is available in various sizes and formats to meet the specific needs of different research applications.