NUAK1 Polyclonal Antibody

Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by PKB/AKT1 during glucose starvation. Activated by phosphorylation on Thr-211 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,Involved in tolerance to glucose starvation. Phosphorylates ATM. Suppresses Fas-induced apoptosis by phosphorylation of CASP6, thus suppressing the activation of the caspase and the subsequent cleavage of CFLAR.,Belongs to the protein kinase superfamily.,Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.,Contains 1 protein kinase domain.,tissue specificity:Expressed at high levels in heart and brain, and at lower levels in skeletal muscle, kidney, ovary, placenta, lung and liver.,

The NUAK1 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of NUAK1 protein expression in various biological samples. This antibody has been meticulously developed using advanced techniques to ensure exceptional sensitivity and specificity.

NUAK1, also known as AMPK-related protein kinase 5 (ARK5), is a serine/threonine kinase that plays a crucial role in cellular processes such as cell proliferation, survival, and metabolism. It is involved in the regulation of various signaling pathways, including the AMP-activated protein kinase (AMPK) pathway, which is essential for maintaining cellular energy homeostasis.

The NUAK1 Polyclonal Antibody has been rigorously validated for its performance in multiple applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other related proteins, ensuring accurate and reliable results.

With its high affinity and specificity, this antibody enables researchers to investigate the expression and localization of NUAK1 in different tissues and cell types. Its exceptional sensitivity allows for the detection of low-abundance NUAK1 protein, facilitating the study of its role in various physiological and pathological processes.

The NUAK1 Polyclonal Antibody is supplied as a liquid formulation, making it convenient and easy to use. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps. The antibody is available in various sizes to accommodate different experimental requirements.

In summary, the NUAK1 Polyclonal Antibody is a valuable tool for researchers studying NUAK1 protein expression and its functional implications. Its high specificity, sensitivity, and ease of use make it an ideal choice for a wide range of applications in the field of molecular biology and biomedical research.