NSE2 Polyclonal Antibody

E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair.,pathway:Protein modification; protein sumoylation.,PTM:Sumoylated, possibly via autosumoylation.,Belongs to the NSE2 family.,Contains 1 SP-RING-type zinc finger.,subunit:Component of the SMC5-SMC6 complex which consists of SMC5, SMC6, NSMCE2/MMS21 and probably NSMCE1.,

The NSE2 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of NSE2 protein in various biological samples. This antibody has been meticulously developed using advanced immunization techniques and exhibits exceptional affinity and selectivity towards NSE2.

With its superior performance characteristics, the NSE2 Polyclonal Antibody offers researchers a reliable and accurate means to investigate the expression and localization of NSE2 in different tissues and cell types. Its robustness and versatility make it suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The NSE2 Polyclonal Antibody is manufactured under stringent quality control measures to ensure batch-to-batch consistency and reproducibility. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation.

Furthermore, this antibody demonstrates minimal cross-reactivity with other proteins, ensuring specific and reliable results. Its high sensitivity allows for the detection of low-abundance NSE2 protein levels, enabling researchers to explore its potential role in various physiological and pathological processes.

In summary, the NSE2 Polyclonal Antibody is a valuable tool for researchers seeking to investigate the expression and function of NSE2 protein. Its exceptional specificity, sensitivity, and ease of use make it an indispensable asset in the field of molecular biology and biomedical research.