Nrf2 Rabbit Polyclonal Antibody

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.

The Nrf2 Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Nrf2 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the N-terminal region of human Nrf2 protein. The antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Nrf2 Rabbit Polyclonal Antibody is a valuable tool for researchers studying the role of Nrf2 in oxidative stress, inflammation, and cancer. Nrf2 is a transcription factor that plays a critical role in the regulation of cellular defense mechanisms against oxidative stress and other environmental insults. Dysregulation of Nrf2 has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.

The Nrf2 Rabbit Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using a protein A column. The antibody is provided in a liquid format, which can be easily diluted in various buffers for use in different applications. The antibody has been validated for its specificity and sensitivity in various cell lines and tissues, including human, mouse, and rat.

In summary, the Nrf2 Rabbit Polyclonal Antibody is a highly specific and sensitive antibody that is ideal for the detection of Nrf2 protein in various biological samples. This antibody is a valuable tool for researchers studying the role of Nrf2 in oxidative stress, inflammation, and cancer.