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SKU:BT-AP11967

NOX4 Polyclonal Antibody

NOX4 Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
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This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.

The NOX4 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of NOX4 protein expression in various biological samples. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reliability.

NOX4, also known as NADPH oxidase 4, is a member of the NOX family of enzymes that play a crucial role in the generation of reactive oxygen species (ROS). It is primarily expressed in the kidney, lung, and vascular endothelial cells, where it is involved in various physiological and pathological processes, including cell signaling, oxidative stress, and inflammation.

The NOX4 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other NOX family members, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps. The NOX4 Polyclonal Antibody is compatible with a wide range of detection systems and can be used in both research and clinical applications.

In summary, the NOX4 Polyclonal Antibody is a highly reliable and specific tool for the detection and quantification of NOX4 protein expression. Its exceptional performance and ease of use make it an ideal choice for researchers and clinicians working in the field of oxidative stress, inflammation, and related areas of study.

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