NOS1(Phospho Ser852) Polyclonal Antibody

The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms

The NOS1 (Phospho Ser852) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of NOS1 protein phosphorylated at Ser852. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

NOS1, also known as neuronal nitric oxide synthase, is an enzyme that plays a crucial role in the production of nitric oxide (NO) in the nervous system. Phosphorylation of NOS1 at Ser852 has been implicated in various physiological and pathological processes, including neuronal signaling, synaptic plasticity, and neurodegenerative diseases.

The NOS1 (Phospho Ser852) Polyclonal Antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other phosphorylated or non-phosphorylated forms of NOS1, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is recommended for use in various research applications, including but not limited to, studying the role of NOS1 phosphorylation in neuronal function, investigating the mechanisms underlying neurodegenerative diseases, and exploring potential therapeutic targets.

With its exceptional specificity, sensitivity, and reliability, the NOS1 (Phospho Ser852) Polyclonal Antibody is an indispensable tool for researchers in the field of neuroscience and related disciplines. Trust in its performance to advance your understanding of NOS1 signaling and its implications in various physiological and pathological processes.