NNT-1 Polyclonal Antibody

This gene is a member of the glycoprotein (gp)130 cytokine family and encodes cardiotrophin-like cytokine factor 1 (CLCF1). CLCF1 forms a heterodimer complex with cytokine receptor-like factor 1 (CRLF1). This dimer competes with ciliary neurotrophic factor (CNTF) for binding to the ciliary neurotrophic factor receptor (CNTFR) complex, and activates the Jak-STAT signaling cascade. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. CLCF1 is a potent neurotrophic factor, B-cell stimulatory agent and neuroendocrine modulator of pituitary corticotroph function. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine. Alternative splicing results in multiple transcript variants encodin

The NNT-1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of NNT-1 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the NNT-1 protein. It has been extensively validated for its specificity and affinity, ensuring reliable and reproducible results.

The NNT-1 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes the NNT-1 protein with high specificity, exhibiting minimal cross-reactivity with other related proteins. This antibody enables accurate and precise detection of NNT-1 protein expression levels, facilitating comprehensive studies on its biological functions and regulatory mechanisms.

With its superior sensitivity, the NNT-1 Polyclonal Antibody allows for the detection of low-abundance NNT-1 protein in samples with limited availability. Its robust performance ensures reliable and reproducible results, making it an ideal choice for both qualitative and quantitative analysis. The antibody is supplied as a liquid formulation, ready for immediate use, eliminating the need for time-consuming reconstitution steps.

The NNT-1 Polyclonal Antibody is manufactured under strict quality control standards, ensuring consistent and reliable performance. It is provided in a convenient size, allowing for multiple experiments without compromising its quality. This antibody is an essential tool for researchers and scientists studying the role of NNT-1 protein in various biological processes, including development, metabolism, and disease progression.

In summary, the NNT-1 Polyclonal Antibody is a highly specific and sensitive reagent that enables accurate detection and quantification of NNT-1 protein. Its exceptional performance, reliability, and ease of use make it an invaluable tool for researchers in the field of molecular biology and biomedical sciences.