MUC5A Polyclonal Antibody

The cysteine residues in the Cys-rich subdomain repeats are not involved in disulfide bonding.,Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particules that are subsequently removed by the mucocilary system.,PTM:C-, O- and N-glycosylated. O-glycosylated on the Thr-/Ser-rich tandem repeats. C-mannosylation in the Cys-rich subdomains may be required for proper folding of these regions and for export from the endoplasmic reticulum during biosynthesis.,PTM:Proteolytic cleavage in the C-terminal is initiated early in the secretory pathway and does not involve a serine protease. The extent of cleavage is increased in the acidic parts of the secretory pathway. Cleavage generates a reactive group which could link the protein to a primary amide.,Contains 1 CTCK (C-terminal cystine knot-like) domain.,Contains 2 VWFC domains.,Contains 4 VWFD domains.,subunit:Multimeric. Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD).,tissue specificity:Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum.,

The MUC5A Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of MUC5A protein expression in various biological samples. This antibody is produced through a rigorous process of immunization using a purified recombinant MUC5A protein, ensuring its high affinity and specificity towards the target antigen.

With its exceptional performance, this polyclonal antibody offers researchers a reliable and accurate means to investigate the role and function of MUC5A in different physiological and pathological processes. It can be utilized in a wide range of applications, including immunohistochemistry, western blotting, and ELISA, enabling comprehensive analysis of MUC5A expression and localization in tissues and cells.

The MUC5A Polyclonal Antibody exhibits excellent sensitivity, allowing for the detection of even low levels of MUC5A protein. Its robust performance ensures reliable and reproducible results, making it an ideal choice for both qualitative and quantitative studies. Furthermore, this antibody demonstrates minimal cross-reactivity with other related proteins, ensuring specificity and reducing the risk of false-positive results.

This product is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without the need for frequent reordering. The MUC5A Polyclonal Antibody is manufactured under strict quality control standards, ensuring consistent performance and batch-to-batch reproducibility.

In summary, the MUC5A Polyclonal Antibody is a valuable tool for researchers seeking to investigate the expression and function of MUC5A protein. Its high specificity, sensitivity, and reliability make it an indispensable asset in various research areas, including cancer biology, respiratory diseases, and mucosal immunology.