MRP5 Polyclonal Antibody

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside

The MRP5 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of the MRP5 protein. This antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity. The MRP5 Polyclonal Antibody is ideal for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The MRP5 protein is a member of the ATP-binding cassette (ABC) transporter family, which plays a critical role in the transport of various molecules across cell membranes. The MRP5 protein is involved in the transport of a wide range of substrates, including drugs, toxins, and endogenous compounds. The MRP5 Polyclonal Antibody is designed to specifically recognize the MRP5 protein, making it an essential tool for researchers studying the function and regulation of this important transporter protein.

The MRP5 Polyclonal Antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity. This antibody is highly specific to the MRP5 protein and does not cross-react with other members of the ABC transporter family. The MRP5 Polyclonal Antibody is also highly sensitive, allowing for the detection of low levels of the MRP5 protein in a variety of sample types.

In summary, the MRP5 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of the MRP5 protein. This antibody is ideal for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. The MRP5 Polyclonal Antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity, making it an essential tool for researchers studying the function and regulation of the MRP5 protein.