MLL2 Polyclonal Antibody

The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome.

The MLL2 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of MLL2 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human MLL2 protein. The resulting polyclonal antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence applications.

The MLL2 protein is a histone methyltransferase that plays a crucial role in the regulation of gene expression and development. Mutations in the MLL2 gene have been associated with various human diseases, including Kabuki syndrome, developmental delay, and cancer. Therefore, the MLL2 Polyclonal Antibody is an essential tool for researchers studying the function and regulation of MLL2 protein in normal and disease states.

This antibody is supplied as a purified IgG fraction, which has been affinity-purified using a protein A column. It is provided in a liquid format and can be used directly in various applications without the need for further purification. The MLL2 Polyclonal Antibody is available in different sizes and formats to meet the specific needs of researchers.

In summary, the MLL2 Polyclonal Antibody is a reliable and high-quality antibody that enables the detection of MLL2 protein in various biological samples. Its specificity and sensitivity make it an essential tool for researchers studying the function and regulation of MLL2 protein in normal and disease states.