MerTK/Tyro3(Phospho Tyr749/681) Polyclonal Antibody

This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

The MerTK/Tyro3(Phospho Tyr749/681) Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of MerTK and Tyro3 proteins phosphorylated at Tyr749 and Tyr681 residues. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

The MerTK and Tyro3 receptor tyrosine kinases play crucial roles in various cellular processes, including cell survival, proliferation, and differentiation. Phosphorylation of specific tyrosine residues in these proteins is known to regulate their activity and downstream signaling pathways. Therefore, the ability to accurately detect and quantify the phosphorylation status of MerTK and Tyro3 is essential for understanding their functional roles in physiological and pathological conditions.

The MerTK/Tyro3(Phospho Tyr749/681) Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various experimental settings, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated forms of MerTK and Tyro3, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is recommended for use in both basic research and clinical applications, including the study of cancer, neurodegenerative diseases, and immune disorders.

In summary, the MerTK/Tyro3(Phospho Tyr749/681) Polyclonal Antibody is a valuable tool for researchers and clinicians interested in investigating the phosphorylation status and functional roles of MerTK and Tyro3 proteins. Its high specificity, sensitivity, and versatility make it an essential component of any study involving these important signaling molecules.