MEP1B Polyclonal Antibody

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.

The MEP1B Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for the detection of MEP1B protein in various biological samples. This antibody has been produced using a polyclonal approach, which ensures a high degree of specificity and sensitivity. The MEP1B Polyclonal Antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The MEP1B Polyclonal Antibody is a valuable tool for researchers studying the role of MEP1B in various biological processes, including protein degradation, cell signaling, and apoptosis. This antibody has been shown to recognize MEP1B from a wide range of species, including human, mouse, and rat.

The MEP1B Polyclonal Antibody is supplied as a liquid solution in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. This antibody is available in various sizes to meet the needs of different research applications.

Overall, the MEP1B Polyclonal Antibody is a reliable and high-quality antibody that is ideal for the detection of MEP1B protein in various biological samples. Its high specificity and sensitivity make it an excellent choice for researchers studying the role of MEP1B in various biological processes.