MEK4 Rabbit Polyclonal Antibody(F194)

This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.

The MEK4 Rabbit Polyclonal Antibody (F194) is a highly specific and sensitive antibody designed for the detection and quantification of MEK4 protein in various biological samples. This antibody has been extensively validated for its performance in Western blotting and immunohistochemistry applications.

The MEK4 protein, also known as MAP2K4, is a crucial component of the mitogen-activated protein kinase (MAPK) signaling pathway. It plays a pivotal role in cellular processes such as cell proliferation, differentiation, and apoptosis. Dysregulation of the MAPK pathway, including MEK4, has been implicated in various diseases, including cancer.

The MEK4 Rabbit Polyclonal Antibody (F194) has been developed using high-quality rabbit polyclonal antibodies that specifically recognize the MEK4 protein. It exhibits excellent sensitivity and specificity, ensuring accurate and reliable results. This antibody has been validated using a wide range of cell lines and tissue samples, demonstrating its robust performance across different experimental conditions.

In Western blotting, the MEK4 Rabbit Polyclonal Antibody (F194) shows a strong and specific band at the expected molecular weight of MEK4 protein. It can detect endogenous levels of MEK4 protein in various cell lysates and tissue extracts. Additionally, this antibody has been successfully used in immunohistochemistry to visualize the subcellular localization of MEK4 protein in tissue sections.

The MEK4 Rabbit Polyclonal Antibody (F194) is supplied as a liquid formulation, making it convenient and easy to use. It is provided in a 100 µg size, ensuring an ample amount for multiple experiments. This antibody has been rigorously tested for its stability and quality, guaranteeing consistent performance over time.

In summary, the MEK4 Rabbit Polyclonal Antibody (F194) is a reliable and high-quality tool for the detection and quantification of MEK4 protein. Its exceptional sensitivity and specificity make it an ideal choice for researchers studying the MAPK signaling pathway and its involvement in various diseases.